Publications
Publications from Postdoctoral, Graduate, and Undergraduate work
Asymmetric Hydroamination Using Oxidative Radical Initiation in Flavin Enzymes
Brown, A. C.; Del Angel Aguilar, C. E; Raps, F. C.; Riehl, P. S.; Hyster, T. K.*
J. Am. Chem. Soc. (2026). DOI: 10.1021/jacs.6c04368
10.1021/jacs.6c04368
The Influence of Heterometals on Dinitrogen Binding at Synthetic Iron-Sulfur Clusters
Wu, T.†; Ehweiner, M.†; Brown, A. C.; McSkimming, A.; Suess, D. L. M.*
Chem, accepted.
In Press
Molybdenum Doping Enhances Backbonding at Neighboring Iron Centers in Iron-Sulfur Clusters
Brown, A. C.; MacMillan, S. N.; McSkimming, A.; Leshchev, D.; Stavitski, E.; Lancaster, K. M.*; Suess, D. L. M.*
Chem, accepted.
In Press
Stereoselective Photoenzymatic Hydroarylation for the Construction of Quaternary Stereocenters
Raps, F. C†; Jin, C. A.†; Brown, A. C.; Sorigué, D.; Hyster, T. K.*
J. Am. Chem. Soc., 147, 40547–40553 (2025).
10.1021/jacs.5c12440
Activation of Strong π-Acids at [Fe4S4]+ Clusters Enabled by a Noncanonical Electronic Structure
Brown, A. C.; Thompson, N. B.; Suess, D. L. M.*
J. Am. Chem. Soc., 146, 34080-34091 (2024).
10.1021/jacs.4c13490
An Iron-Sulfur Cluster with a Highly Pyramidalized Three-Coordinate Iron Center and a Negligible Affinity for Dinitrogen
Brown, A. C.; Suess, D. L. M.*
J. Am. Chem. Soc., 145, 20088-20096 (2023).
10.1021/jacs.3c07677
A General Method for Metallocluster Site-Differentiation
Bostelaar, T. M.; Brown, A. C.; Sridharan, A; Suess, D. L. M.*
Nat. Synth., 2, 740-748 (2023).
10.1038/s44160-023-00286-7
An Open-Cuboidal [Fe3S4] Cluster Characterized in Both Biologically Relevant Redox States
Brown, A. C.; Suess, D. L. M.*
J. Am. Chem. Soc., 145, 2075-2080 (2023).
10.1021/jacs.2c13126
Valence Localization in Alkyne and Alkene Adducts of Synthetic [Fe4S4]+ Clusters
Brown, A. C.; Suess, D. L. M.*
Inorg. Chem. (invited Forum Article), 62, 1911-1918 (2023).
10.1021/acs.inorgchem.2c01353
Pyrogallate-Based Metal-Organic Framework with a Two-Dimensional Secondary Building Unit
Kampouri, S.; Zhang, M.; Chen, T.; Oppenheim, J. J.; Brown, A. C.; Payne, M. T.; Andrews, J. L.; Sun, J.; Dincǎ, M.*
Angew. Chem. Int. Ed. 61, e202213960 (2022). 
10.1002/anie.202213960
Reversible Alkyl-Group Migration between Iron and Sulfur in [Fe4S4] Clusters
Ye, M.; Brown, A. C.; Suess, D. L. M.*
J. Am. Chem. Soc., 144, 13184–13195 (2022).
10.1021/jacs.2c03195
Evidence for Low-Valent Electronic Configurations in Iron-Sulfur Clusters
Brown, A. C.; Thompson, N. B.; Suess, D. L. M.*
J. Am. Chem. Soc., 144, 9066–9073 (2022).
10.1021/jacs.2c01872
A Terminal Imido Complex of an Iron–Sulfur Cluster
Sridharan, A.; Brown, A. C.; Suess, D. L. M.*
Angew. Chem. Int. Ed. 60, 12802–12806 (2021).
10.1002/anie.202102603
Synthetic Iron–Sulfur Clusters
Brown, A. C.; Suess, D. L. M.*
Book chapter in Comprehensive Coordination Chemistry III, Vol. 8; Constable, E. C., Parkin, G., Que, L., Eds.; Elsevier, Amsterdam, 2021; pp 134–156.
10.1016/B978-0-08-102688-5.00053-2
Reversible Formation of Alkyl Radicals at [Fe4S4] Clusters and Its Implications for Selectivity in Radical SAM Enzymes
Brown, A. C.; Suess, D. L. M.*
J. Am. Chem. Soc. 142, 14240–14248 (2020).
10.1021/jacs.0c05590
A Synthetic Model of Enzymatic [Fe4S4]–Alkyl Intermediates
Ye, M.; Thompson, N. B.; Brown, A. C.; Suess, D. L. M.*
J. Am. Chem. Soc. 141, 13330–13335 (2019).
10.1021/jacs.9b06975
Metal Bonding with 3d and 6d Orbitals: An EPR and ENDOR Spectroscopic Investigation of Ti3+-Al and Th3+-Al Heterobimetallic Complexes
Rao, G.; Altman, A. B.; Brown, A. C.; Tao, L.; Stitch, T. A.; Arnold, J.;* Britt, R. D.*
Inorg. Chem. 58, 7978–7988 (2019).
10.1021/acs.inorgchem.9b00720
Controlling Substrate Binding to Fe4S4 Clusters Through Remote Steric Effects
Brown, A. C.; Suess, D. L. M.*
Inorg. Chem. 58, 5273–5280 (2019).
10.1021/acs.inorgchem.9b00360
Chemical Structure and Bonding in a Thorium(III)-Aluminum Heterobimetallic Complex
Altman, A. B.; Brown, A. C.; Rao, G.; Lohrey, T. D.; Britt, R. D.; Maron, L.; Minasian, S. G.; Shuh, D. K.; Arnold, J.*
Chem. Sci. 9, 4317–4324 (2018).
10.1039/C8SC01260A
Hydride Oxidation from a Titanium-Aluminum Bimetallic Complex: Insertion, Thermal and Electrochemical Reactivity
Brown, A. C.†; Altman, A. B.†; Lohrey, T. D.; Hohloch, S.; Arnold, J.*
Chem. Sci. 8, 5153–5160 (2017).
10.1039/C7SC01835E
The Brown Lab

UC Berkeley College of Chemistry
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Berkeley, CA 94720